Single-nuclei RNAseq datasets

The Abbott lab in collaboration with the Campbell lab (UVA, Department of Biology) has published the results from single-nuclei RNA-sequencing of over 100K cells from the ventrolateral medulla of mice. The paper describing our results has been published in The Journal of Neuroscience (https://doi.org/10.1523/JNEUROSCI.2211-23.2024). The data from this project can be explored through the Broad Institute Single Cell Portal. The data and code for our analysis are available through Zenodo.

Broad Institute Single Cell Portal links for DEG clustering

All cells
All neurons
Astrocytes
Serotonin neurons
CARTPT/C1/A1 neurons

Code
zenodo.org/records/10048289 – The deposited file contains the R code used to process, cluster, and visualize the clustered data with Seurat software package for R.